Application

Pharmaceutical Industry

PVP (K30/K90) and Carbomer (971P/974P) as tablet binders, film coatings, and controlled-release matrix systems; PVPP as a tablet superdisintegrant; 2-Pyrrolidone as a key intermediate in Piracetam synthesis. Full EP/USP compliance and batch CoA across the line.

Pharmaceutical Industry — application scenario

Related Products

PVP (Polyvinylpyrrolidone) →Carbomer (Polyacrylic Acid) →PVPP (Crospovidone / Polyvinylpolypyrrolidone) →2-Pyrrolidone (2-P / α-Pyrrolidinone) →

Our PVP, Carbomer, PVPP, and 2-Pyrrolidone products serve as essential excipients and intermediates in pharmaceutical manufacturing, meeting the stringent quality requirements of pharmacopoeial standards.

Tablet Binding & Film Coating with PVP

PVP is one of the most effective binders in wet granulation, offering excellent cohesive properties at low concentrations (2–5%). K-values K30 and K90 are the industry standards, and PVP also functions as a film-coating agent and matrix former for controlled-release systems.

Controlled-Release Matrices with Carbomer

Carbomer 971P and 974P create crystal-clear aqueous gels and hydrophilic matrix systems ideal for topical drug delivery and controlled-release tablet matrices. Their high viscosity at low concentrations (0.5–2%) provides elegant formulation aesthetics and predictable release profiles.

Superdisintegration with PVPP

PVPP (crospovidone) rapidly disintegrates tablets through strong capillary action and swelling capacity, improving dissolution and bioavailability — particularly valuable in direct-compression formats where fast breakup is critical.

2-Pyrrolidone as a Synthesis Intermediate

2-Pyrrolidone is a key intermediate in the synthesis of Piracetam and other active ingredients, and doubles as a high-boiling polar solvent in pharmaceutical manufacturing routes.

Frequently Asked Questions

What PVP grade is most commonly used in tablet binding?
PVP K30 is the most widely used grade for wet granulation and direct compression tablet binding. PVP K90 is preferred for sustained-release formulations.
Is Carbomer suitable for ophthalmic preparations?
Yes, Carbomer 971P and 974P are commonly used in artificial tears and ophthalmic gels due to their high clarity and biocompatibility.
What role does PVPP play in tablet formulation?
PVPP (crospovidone) is a superdisintegrant — its insoluble, highly porous structure rapidly absorbs water and swells, breaking tablets apart on contact with fluid and improving dissolution rate and bioavailability, especially in direct-compression formats.
How is 2-Pyrrolidone used in pharmaceutical synthesis?
2-Pyrrolidone is a key intermediate in the synthesis of Piracetam, and serves as a high-boiling solvent in certain active-ingredient manufacturing routes.
What documentation do you provide for pharmaceutical grades?
We provide full CoA (Certificate of Analysis), MSDS, TDS, and can arrange DMF (Drug Master File) access upon request.
Do you supply EP or USP grade polymers?
Both. Our PVP, Carbomer, and PVPP are available in EP (European Pharmacopoeia) and USP (United States Pharmacopoeia) compliant grades, with batch-level documentation for regulatory filings.